The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Apr. 21, 2015
Applicants:
Taisho Pharmaceutical Co., Ltd., Toshima-ku, Tokyo, JP;
Toyama Chemical Co., Ltd., Shinjuku-ku, Tokyo, JP;
Inventors:
Hajime Takashima, Toshima-ku, JP;
Risa Tsuruta, Toshima-ku, JP;
Tetsuya Yabuuchi, Toshima-ku, JP;
Yusuke Oka, Toshima-ku, JP;
Hiroki Urabe, Toshima-ku, JP;
Yoichiro Suga, Toshima-ku, JP;
Masato Takahashi, Toshima-ku, JP;
Fumito Uneuchi, Toshima-ku, JP;
Hironori Kotsubo, Toyama, JP;
Muneo Shoji, Toyama, JP;
Yasuko Kawaguchi, Toyama, JP;
Assignees:
TOYAMA CHEMICAL CO., LTD., Tokyo, JP;
TAISHO PHARMACEUTICAL CO., LTD, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 259/06 (2006.01); C07C 323/62 (2006.01); C07D 305/06 (2006.01); C07D 307/14 (2006.01); C07D 317/30 (2006.01); C07D 319/18 (2006.01); C07D 295/08 (2006.01); C07D 285/12 (2006.01); C07D 271/12 (2006.01); C07D 265/30 (2006.01); C07D 263/14 (2006.01); C07D 261/08 (2006.01); C07D 235/04 (2006.01); C07D 233/61 (2006.01); C07D 231/12 (2006.01); C07D 217/04 (2006.01); C07D 211/14 (2006.01); C07D 209/08 (2006.01); C07D 207/10 (2006.01); C07D 205/04 (2006.01); C07C 233/83 (2006.01); C07C 271/22 (2006.01); C07C 271/28 (2006.01); C07C 311/08 (2006.01); C07C 317/28 (2006.01); C07C 317/44 (2006.01); C07C 323/41 (2006.01); C07D 205/12 (2006.01); C07D 207/12 (2006.01); C07D 207/27 (2006.01); C07D 207/327 (2006.01); C07D 209/12 (2006.01); C07D 209/14 (2006.01); C07D 209/44 (2006.01); C07D 209/52 (2006.01); C07D 211/18 (2006.01); C07D 211/38 (2006.01); C07D 211/46 (2006.01); C07D 211/56 (2006.01); C07D 211/70 (2006.01); C07D 213/38 (2006.01); C07D 213/40 (2006.01); C07D 213/54 (2006.01); C07D 213/61 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07D 213/70 (2006.01); C07D 213/74 (2006.01); C07D 213/81 (2006.01); C07D 215/14 (2006.01); C07D 217/12 (2006.01); C07D 231/56 (2006.01); C07D 257/04 (2006.01); C07D 263/32 (2006.01); C07D 263/56 (2006.01); C07D 265/38 (2006.01); C07D 267/10 (2006.01); C07D 277/20 (2006.01); C07D 277/30 (2006.01); C07D 277/62 (2006.01); C07D 277/66 (2006.01); C07D 295/12 (2006.01); C07D 295/14 (2006.01); C07D 295/16 (2006.01); C07D 305/08 (2006.01); C07D 307/18 (2006.01); C07D 307/52 (2006.01); C07D 307/54 (2006.01); C07D 307/78 (2006.01); C07D 307/82 (2006.01); C07D 307/87 (2006.01); C07D 309/04 (2006.01); C07D 309/14 (2006.01); C07D 317/60 (2006.01); C07D 319/20 (2006.01); C07D 333/24 (2006.01); C07D 405/06 (2006.01); C07D 413/06 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 487/08 (2006.01); C07D 491/20 (2006.01); C07D 498/08 (2006.01); C07F 9/09 (2006.01); C07C 235/84 (2006.01); C07C 237/36 (2006.01); C07C 309/30 (2006.01); C07D 265/36 (2006.01); C07D 307/81 (2006.01); C07D 498/04 (2006.01); C07D 241/04 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
C07C 233/83 (2013.01); C07C 235/84 (2013.01); C07C 237/36 (2013.01); C07C 259/06 (2013.01); C07C 271/22 (2013.01); C07C 271/28 (2013.01); C07C 309/30 (2013.01); C07C 311/08 (2013.01); C07C 317/28 (2013.01); C07C 317/44 (2013.01); C07C 323/41 (2013.01); C07C 323/62 (2013.01); C07D 205/04 (2013.01); C07D 205/12 (2013.01); C07D 207/10 (2013.01); C07D 207/12 (2013.01); C07D 207/27 (2013.01); C07D 207/327 (2013.01); C07D 209/08 (2013.01); C07D 209/12 (2013.01); C07D 209/14 (2013.01); C07D 209/44 (2013.01); C07D 209/52 (2013.01); C07D 211/14 (2013.01); C07D 211/18 (2013.01); C07D 211/38 (2013.01); C07D 211/46 (2013.01); C07D 211/56 (2013.01); C07D 211/70 (2013.01); C07D 213/38 (2013.01); C07D 213/40 (2013.01); C07D 213/54 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 213/70 (2013.01); C07D 213/74 (2013.01); C07D 213/81 (2013.01); C07D 215/14 (2013.01); C07D 217/04 (2013.01); C07D 217/12 (2013.01); C07D 231/12 (2013.01); C07D 231/56 (2013.01); C07D 233/61 (2013.01); C07D 235/04 (2013.01); C07D 257/04 (2013.01); C07D 261/08 (2013.01); C07D 263/14 (2013.01); C07D 263/32 (2013.01); C07D 263/56 (2013.01); C07D 265/30 (2013.01); C07D 265/36 (2013.01); C07D 265/38 (2013.01); C07D 267/10 (2013.01); C07D 271/12 (2013.01); C07D 277/20 (2013.01); C07D 277/30 (2013.01); C07D 277/62 (2013.01); C07D 277/66 (2013.01); C07D 285/12 (2013.01); C07D 295/08 (2013.01); C07D 295/12 (2013.01); C07D 295/14 (2013.01); C07D 295/16 (2013.01); C07D 305/06 (2013.01); C07D 305/08 (2013.01); C07D 307/14 (2013.01); C07D 307/18 (2013.01); C07D 307/52 (2013.01); C07D 307/54 (2013.01); C07D 307/78 (2013.01); C07D 307/81 (2013.01); C07D 307/82 (2013.01); C07D 307/87 (2013.01); C07D 309/04 (2013.01); C07D 309/14 (2013.01); C07D 317/30 (2013.01); C07D 317/60 (2013.01); C07D 319/18 (2013.01); C07D 319/20 (2013.01); C07D 333/24 (2013.01); C07D 405/06 (2013.01); C07D 413/06 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/08 (2013.01); C07D 491/20 (2013.01); C07D 498/04 (2013.01); C07D 498/08 (2013.01); C07F 9/091 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2101/16 (2013.01); C07C 2101/18 (2013.01); C07C 2102/08 (2013.01);
Abstract
Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria includingand its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof.