The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Sep. 10, 2007
David H. Margolin, Somerville, MA (US);
Walter Hong, Whippany, NJ (US);
Alasdair J. Coles, Cambridge, GB;
Alastair Compston, Cambridge, GB;
Ze'ev Shaked, San Antonio, TX (US);
David H. Margolin, Somerville, MA (US);
Walter Hong, Whippany, NJ (US);
Alasdair J. Coles, Cambridge, GB;
Alastair Compston, Cambridge, GB;
Ze'ev Shaked, San Antonio, TX (US);
GENZYME CORPORATION, Cambridge, MA (US);
ALCAFLEU MANAGEMENT GMBH & CO. KG., Ot Waltersdorf, DE;
Abstract
A method for treatment of multiple sclerosis (MS) with Campath-1H with significant efficacy and a favorable safety profile is described, which offers an acceptable benefit/risk ratio. Especially described is the use of Campath-1H (alemtuzumab) for the production of a medicament for the treatment of multiple sclerosis (MS), comprising a first treatment cycle followed by at least one further treatment cycle of Campath-1H (alemtuzumab), in which each treatment cycle comprises 1-5 daily doses which are applied on consecutive days, wherein the daily dose is >0 and ≦12 mg, and wherein each treatment cycle is separated from the next cycle by at least 1-24 months. Also described are treatment regimens comprising the administration of less than 12 mg/day of Campath-1H for a period of 1-5 consecutive days.