The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2016

Filed:

Dec. 20, 2013
Applicant:

Laboratoire Medidom SA, Samen, CH;

Inventors:

Stefano Carlino, Collombey, CH;

René-Pierre Bunter, Venthone, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7032 (2006.01); A61P 25/00 (2006.01); C07H 1/06 (2006.01); C07H 15/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7032 (2013.01); C07H 15/10 (2013.01);
Abstract

A process for preparing pure monosialoganglioside GM1 in the form of its sodium salt. There is provided a process for the isolation and purification of monosialoganglioside GM1 comprising (a) separation of GM1 from a lipidic mixture containing the monosialoganglioside GM1 as the main ganglioside component by ion exchange column-chromatography using an eluent comprising potassium or caesium ions, (b) recovery of the solute from the eluted solution, (c) diafiltration of an aqueous solution of the recovered solute, and (d) second diafiltration after the addition of 1 M NaCl, and recovering GM1. The purity level of GM1 obtained is higher than 99.0%.


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Carlino, Stefano. (2016). Method for treatment of disease with pure porcine monosialoganglioside gm1 (U.S. Patent No. 9498490). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9498490

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