The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2016

Filed:

Apr. 02, 2013
Applicant:

Ab Biosciences, Inc., Allston, MA (US);

Inventors:

Hsiu-Ching Chang, Lexington, MA (US);

Yen-Ming Hsu, Lexington, MA (US);

Jeng-Shin Lee, Lincoln, MA (US);

Assignee:

AB BIOSCIENCES, INC., Allston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/22 (2006.01); G01N 33/68 (2006.01); G01N 33/94 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/241 (2013.01); G01N 33/94 (2013.01); C07K 2317/40 (2013.01); C07K 2317/565 (2013.01);
Abstract

The present invention provides novel, rationally designed human control antibodies for use in various in vivo and in vitro applications. The antibodies of the present invention have well characterized variable domains that have been designed to minimize or eliminate antigen binding without altering gross antibody structure. Using the antibodies of the present invention in various assays allows researchers to distinguish effects that result from specific antigen-antibody interactions from other, non-specific antibody effects.


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