The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2016

Filed:

Feb. 03, 2012
Applicants:

Soon Chye NG, Singapore, SG;

Swee Lian Liow, Singapore, SG;

Naiqing Chen, Singapore, SG;

Yen Wah Tong, Singapore, SG;

Saif Abdul Kadir Khan, Singapore, SG;

Boon Sing Fang, Singapore, SG;

Inventors:

Soon Chye Ng, Singapore, SG;

Swee Lian Liow, Singapore, SG;

Naiqing Chen, Singapore, SG;

Yen Wah Tong, Singapore, SG;

Saif Abdul Kadir Khan, Singapore, SG;

Boon Sing Fang, Singapore, SG;

Assignee:

Neobios PTE LTD, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); C12N 5/076 (2010.01); G01N 33/483 (2006.01); C12M 1/00 (2006.01); B01L 3/00 (2006.01); G01N 33/487 (2006.01); G01N 15/14 (2006.01); C12M 3/06 (2006.01); C12N 5/071 (2010.01); A61D 19/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/4833 (2013.01); B01L 3/5027 (2013.01); C12M 47/04 (2013.01); A61D 19/00 (2013.01); B01L 3/50273 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); C12M 23/16 (2013.01); C12N 5/061 (2013.01); C12N 5/0612 (2013.01); G01N 15/147 (2013.01); G01N 33/487 (2013.01); G01N 2015/149 (2013.01); Y10T 29/49826 (2015.01);
Abstract

According to embodiments of the present invention, a passive counter flow free microfluidic device for sorting a sample of flagellated cells is provided. The passive counter flow free microfluidic device includes an input reservoir configured to receive the sample of flagellated cells, an output reservoir positioned downstream of the input reservoir, the output reservoir configured to collect the flagellated cells that are sorted, and a plurality of microchannel sections arranged sequentially and in fluid communication with each other between the input reservoir and the output reservoir, and designed to define a closed microchannel system between the input reservoir and the output reservoir, wherein each microchannel section comprises at least one microchannel, wherein an inlet of the microchannel of a first microchannel section of the plurality of microchannel sections is connected to the input reservoir, wherein an outlet of the microchannel of a last microchannel section of the plurality of microchannel sections is connected to the output reservoir, and wherein, for each microchannel section, the total volume of the microchannels of one microchannel section of the plurality of microchannel sections is larger than that of the respective in said downstream direction subsequent microchannel section of the plurality of microchannel sections for sorting the flagellated cells when the flagellated cells move from the input reservoir to the output reservoir.


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