The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Jan. 13, 2012
Applicants:
Brooke Emerling, Boston, MA (US);
Atsuo Sasaki, Newton, MA (US);
Lewis C. Cantley, Cambridge, MA (US);
Jonathan Hurov, Cambridge, MA (US);
Inventors:
Brooke Emerling, Boston, MA (US);
Atsuo Sasaki, Newton, MA (US);
Lewis C. Cantley, Cambridge, MA (US);
Jonathan Hurov, Cambridge, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12Q 1/48 (2006.01); A61K 31/7105 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); A61K 31/7105 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
The invention features methods for identifying compounds that modulate the activity of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). Inhibitors of PI5P4K can be used in, for example, the treatment or prevention of cell proliferation disorders (e.g., the prevention of tumor cell growth in p53 mutated cancers).