The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Feb. 29, 2012
Applicants:
Benoit Polack, Saint Martin le Vinoux, FR;
Aline Thomas, Meylan, FR;
Inventors:
Benoit Polack, Saint Martin le Vinoux, FR;
Aline Thomas, Meylan, FR;
Assignees:
UNIVERSITE JOSEPH FOURIER (GRENOBLE 1), Grenoble, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); A61K 38/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6432 (2013.01); A61K 38/4846 (2013.01); C12Y 304/21006 (2013.01);
Abstract
The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor.