The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Feb. 24, 2014
Applicant:
Augusta University Research Institute, Inc., Augusta, GA (US);
Inventors:
Lin Mei, Evans, GA (US);
Wen-Cheng Xiong, Evans, GA (US);
Cheng-Yong Shen, Augusta, GA (US);
Yan-Mei Tao, Martinez, GA (US);
Shi-Wen Luo, Augusta, GA (US);
Assignee:
Augusta University Research Institute, Inc., Augusta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/71 (2006.01); C07K 7/08 (2006.01); C07K 14/705 (2006.01); A61K 47/48 (2006.01); C07K 19/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61K 47/48315 (2013.01); C07K 7/08 (2013.01); C07K 14/70596 (2013.01); A61K 38/00 (2013.01);
Abstract
Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length.