The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Jul. 16, 2010
Gary Brian Evans, Normandale, NZ;
Alistair Ian Longshaw, Thorndon, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Northland, NZ;
Gary Brian Evans, Normandale, NZ;
Alistair Ian Longshaw, Thorndon, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Northland, NZ;
Victoria Link Limited, Wellington, NZ;
Albert Einstein College of Medicine, Inc., Bronx, NY (US);
Abstract
The present invention relates to 3-hydroxypyrrolidine compounds of the general formula (I) which are inhibitors of 5'-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds.