The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Feb. 26, 2013
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
William R. Roush, Jupiter, FL (US);
Ronald Rahaim, Palm Beach Gardens, FL (US);
Mathieu Bibian, Creissels, FR;
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 473/34 (2006.01); C07D 473/32 (2006.01); C07D 473/16 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 473/32 (2013.01); C07D 473/16 (2013.01); C07D 473/34 (2013.01); C07D 519/00 (2013.01);
Abstract
The invention provides compounds that inhibit the degradation of Wee1. The compounds of the present invention are generally N-((1H-benzo[d]imidazol-2-yl)methyl)-9H-purin-6-amines. Compounds of the invention can be used for treatment of malconditions in patients for which inhibition of Wee1 is medically indicated, for example cancer, Alzheimer's, neurological disorders, psychiatric disorders, or inflammation-related disorders.