The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2016

Filed:

Mar. 01, 2016
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Jennifer R. Allen, Newbury Park, CA (US);

Jian J. Chen, Camarillo, CA (US);

Michael J. Frohn, Thousand Oaks, CA (US);

Matthew R. Kaller, Ventura, CA (US);

Qingyian Liu, Camarillo, CA (US);

Thomas T. Nguyen, Newbury Park, CA (US);

Alexander J. Pickrell, Westlake Village, CA (US);

Wenyuan Qian, Newbury Park, CA (US);

Robert M. Rzasa, Thousand Oaks, CA (US);

Wenge Zhong, Thousand Oaks, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 471/04 (2006.01); C07D 401/14 (2006.01); A61K 31/497 (2006.01); A61K 45/06 (2006.01); A61K 31/517 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/497 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01);
Abstract

Azetidine and piperidine compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.


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