The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2016

Filed:

Jun. 15, 2012
Applicants:

Joerg Nerkamp, Halle/Saale, DE;

Eva Bosse-doenecke, Halle/Saale, DE;

Arnd Steuernagel, Halle/Saale, DE;

Ulrike Fiedler, Halle/Saale, DE;

Markus Fiedler, Halle/Saale, DE;

Inventors:

Joerg Nerkamp, Halle/Saale, DE;

Eva Bosse-Doenecke, Halle/Saale, DE;

Arnd Steuernagel, Halle/Saale, DE;

Ulrike Fiedler, Halle/Saale, DE;

Markus Fiedler, Halle/Saale, DE;

Assignee:

Scil Proteins GmbH, Halle/Saale, unknown;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); A61K 51/08 (2006.01); C12N 1/14 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); C12N 1/16 (2006.01); C12N 1/20 (2006.01); C07K 14/47 (2006.01); C07K 14/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 51/08 (2013.01); C07K 14/00 (2013.01); C07K 14/47 (2013.01); C12N 1/14 (2013.01); C12N 1/16 (2013.01); C12N 1/20 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); G01N 33/6803 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01); C07K 2319/95 (2013.01);
Abstract

The present invention refers to novel dimeric proteins obtained from modified ubiquitin capable of binding targets with high affinity. The novel dimeric binding proteins comprise a combination of amino acid substitutions and at least one insertion of amino acids in one of the monomers. The invention is further directed to the use of said proteins in medical diagnosis or treatment methods.


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