The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Sep. 03, 2010
Angelo Guglielmotti, Rome, IT;
Beatrice Garrone, Rome, IT;
Alessandro Ble', Aprilia, IT;
Giuseppe Biondi, Castel Gandolfo, IT;
Roberta Petrosemolo, Castel Gandolfo, IT;
Enrica Biondi, Nerviano, IT;
Iacopo Biondi, Castellanza, IT;
Angelo Guglielmotti, Rome, IT;
Beatrice Garrone, Rome, IT;
Alessandro Ble', Aprilia, IT;
Giuseppe Biondi, Castel Gandolfo, IT;
Abstract
The present invention relates to a pharmaceutical composition comprising a combination of 1-benzyl-3-hydroxymethylindazole derivative, a pressure lowering agent selected from ACE-inhibitors, renin inhibitors, ARBs and CCBs, and/or a cholesterol lowering agent selected from statin derivatives. The combination showed an additive and synergistic activity in reducing MCP-1 levels, thus significantly improving inflammatory response inhibition and consequently reducing complications occurring in patients suffering from inflammatory diseases.