The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Jun. 11, 2014
Applicant:
Genelux Corporation, San Diego, CA (US);
Inventors:
Aladar A. Szalay, Highland, CA (US);
Tatyana Timiryasova, Scotrun, PA (US);
Yong A. Yu, San Diego, CA (US);
Qian Zhang, San Diego, CA (US);
Assignee:
Genelux Corporation, San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/285 (2006.01); A61K 35/768 (2015.01); C12P 19/34 (2006.01); A61K 35/744 (2015.01); C12P 21/02 (2006.01); C12N 7/00 (2006.01); C07K 16/40 (2006.01); A61K 35/74 (2015.01); C07K 16/30 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/285 (2013.01); A61K 35/74 (2013.01); A61K 35/744 (2013.01); A61K 35/768 (2013.01); C07K 16/30 (2013.01); C07K 16/40 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12P 19/34 (2013.01); C12P 21/02 (2013.01); A61K 39/00 (2013.01); A61K 48/00 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/24132 (2013.01); C12N 2710/24143 (2013.01); C12N 2710/24161 (2013.01);
Abstract
Therapeutic methods and vaccinia virus therefor are provided. The viruses are designed so that they accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. Combinations of the viruses and anti-cancer agents and uses thereof for treating cancer also are provided.