The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
May. 12, 2011
Thomas J. Gardella, Needham, MA (US);
John T. Potts, Jr., Newton, MA (US);
Harald Jueppner, Lexington, MA (US);
Makoto Okazaki, Tokyo, JP;
Thomas J. Gardella, Needham, MA (US);
John T. Potts, Jr., Newton, MA (US);
Harald Jueppner, Lexington, MA (US);
Makoto Okazaki, Tokyo, JP;
The General Hospital Corporation, Boston, MA (US);
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed.