The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Oct. 08, 2009
Applicants:
Robert P. Beech, Cincinnati, OH (US);
Thomas D. Reed, Arlington, VA (US);
Inventors:
Robert P. Beech, Cincinnati, OH (US);
Thomas D. Reed, Arlington, VA (US);
Assignee:
Intrexon Corporation, Blacksburg, VA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 31/7088 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); C12N 15/86 (2006.01); A61K 38/20 (2006.01); A61K 9/00 (2006.01); A61K 38/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 31/7088 (2013.01); A61K 38/208 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); C12N 15/86 (2013.01); A61K 9/0095 (2013.01); A61K 38/00 (2013.01); A61K 2035/124 (2013.01); A61K 2039/5154 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/002 (2013.01); C12N 2840/206 (2013.01);
Abstract
This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally expressing interleukin-12 (IL-12) and one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals.