The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2016
Filed:
Oct. 08, 2012
Applicants:
Genzyme Corporation, Framingham, MA (US);
The Regents of the University of California, Oakland, CA (US);
Inventors:
Krystof Bankiewicz, Garrett Park, MD (US);
Janet Cunningham, Alameda, CA (US);
Assignees:
Genzyme Corporation, Framingham, MA (US);
The Regents of the University of California, Oakland, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/86 (2006.01); A01N 63/00 (2006.01); A61K 48/00 (2006.01); A61K 31/198 (2006.01); A61K 38/45 (2006.01); A61K 38/51 (2006.01); A61K 47/48 (2006.01); A61K 51/00 (2006.01); A61K 35/761 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 35/761 (2013.01); A61K 38/45 (2013.01); A61K 38/51 (2013.01); A61K 45/06 (2013.01); A61K 47/48776 (2013.01); A61K 48/00 (2013.01); A61K 48/0075 (2013.01); A61K 51/00 (2013.01); A01N 63/00 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01);
Abstract
Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.