The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2016

Filed:

Feb. 07, 2014
Applicant:

The Curators of the University of Missouri, Columbia, MO (US);

Inventors:

James L. Cook, Columbia, MO (US);

Cristi R. Cook, Columbia, MO (US);

Aaron M. Stoker, Columbia, MO (US);

Keiichi Kuroki, Columbia, MO (US);

Bridget Colleen Garner, Athens, GA (US);

Richard Evans, Columbia, MO (US);

Brandon Lee Roller, Naples, FL (US);

Prakash Sidha Jayabalan, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/136 (2013.01); G01N 2800/105 (2013.01); G01N 2800/56 (2013.01);
Abstract

Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.


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