The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2016
Filed:
Nov. 12, 2015
Applicant:
Fondazione Telethon, Rome, IT;
Inventors:
Andrea Ballabio, Naples, IT;
Alessandro Fraldi, Naples, IT;
Assignee:
FOND AZIONE TELETHON, Rome, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C12N 9/14 (2006.01); C07K 14/81 (2006.01); A61K 38/46 (2006.01); C07K 14/775 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/46 (2013.01); A61K 48/0058 (2013.01); C07K 14/775 (2013.01); C07K 14/8125 (2013.01); C12N 9/16 (2013.01); C12Y 301/06013 (2013.01); C12Y 310/01001 (2013.01); A61K 48/005 (2013.01); C07K 2319/02 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention provides for nucleotide sequences encoding for a chimeric sulfatase, viral vectors expressing such sequences for gene therapy and pharmaceutical uses of the chimeric expressed protein. The invention is particularly applied in the therapy of mucopolysaccharidosis, preferably type IIIA.