The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2016

Filed:

Nov. 11, 2010
Applicants:

Ugur Sahin, Mainz, DE;

Ozlem Tureci, Mainz, DE;

Michael Koslowski, Frankfurt, DE;

Korden Walter, Wiesbaden, DE;

Stefan Woll, Nackenheim, DE;

Maria Kreuzberg, Mainz, DE;

Bernd Hubner, Munich, DE;

Michael Erdeljan, Hochheim am Main, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Ozlem Tureci, Mainz, DE;

Michael Koslowski, Frankfurt, DE;

Korden Walter, Wiesbaden, DE;

Stefan Woll, Nackenheim, DE;

Maria Kreuzberg, Mainz, DE;

Bernd Hubner, Munich, DE;

Michael Erdeljan, Hochheim am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01);
Abstract

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing Claudin-6 (CLDN6), including tumor-related diseases such as ovarian cancer, lung cancer, gastric cancer, breast cancer, hepatic cancer, pancreatic cancer, skin cancer, malignant melanoma, head and neck cancer, sarcoma, bile duct cancer, cancer of the urinary bladder, kidney cancer, colon cancer, placental choriocarcinoma, cervical cancer, testicular cancer, and uterine cancer.


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