The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2016

Filed:

May. 22, 2013
Applicant:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Maria R. Parkhurst, Ellicott City, MD (US);

Richard A. Morgan, Columbia, MD (US);

Steven A. Rosenberg, Potomac, MD (US);

Shannon Faith Rosati, Richmond, VA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/18 (2013.01); C07K 16/2809 (2013.01); G01N 33/57492 (2013.01); A61K 38/00 (2013.01); C07K 2317/20 (2013.01); C07K 2317/21 (2013.01); C07K 2319/00 (2013.01); G01N 2333/7051 (2013.01);
Abstract

The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for NY-ESO-1. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a mammal and a method of treating or preventing cancer in a mammal using the inventive TCRs or related materials.


Find Patent Forward Citations

Loading…