The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2016
Filed:
Mar. 13, 2013
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Kevin M. Belyk, Metchun, NJ (US);
Edward Cleator, Whittlesford, GB;
Shen-Chun Kuo, Union, NJ (US);
Peter Emmanuel Maligres, Fanwood, NJ (US);
Bangping Xiang, Bridgewater, NJ (US);
Nobuyoshi Yasuda, Mountainside, NJ (US);
Jianguo Yin, Plainsboro, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 405/06 (2006.01); C07D 487/04 (2006.01); A01N 53/00 (2006.01); C07D 471/20 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A01N 53/00 (2013.01); C07D 405/06 (2013.01); C07D 471/04 (2013.01); C07D 471/20 (2013.01); C07F 7/1804 (2013.01);
Abstract
The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.