The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9487487 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 08, 2016

Filed:

May. 17, 2013
Applicant:

Laurus Labs Private Ltd. Plot No. Ds1, Hyderabad, IN;

Inventors:

Srinivas Simhadri, Hyderabad, IN;

Yaseen Mohammad, Hyderabad, IN;

Venkata S. Indukuri, Hyderabad, IN;

Seeta R. Gorantla, Hyderabad, IN;

Satyanarayana Chava, Hyderabad, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/18 (2006.01);
U.S. Cl.
CPC ...
C07D 215/18 (2013.01);
Abstract

Disclosed is a process for the preparation of montelukast sodium. The process comprises a) reacting 2-(2-(3(S)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-hydroxypropyl)phenyl)-2-propanol with methane sulfonyl chloride and coupling the resultant mesylate compound with 1-(mercaptomethyl)cyclopropane acetic acid in presence of a base and free alkali source followed by saltification with an amine in a single step reaction and b) converting the montelukast amine salt to montelukast sodium salt.


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