The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2016

Filed:

Mar. 11, 2013
Applicants:

Northeastern University, Boston, MA (US);

Copernicus Therapeutics, Inc., Cleveland, OH (US);

Inventors:

Brendan Harmon, Patchogue, NY (US);

Barbara Lee Waszczak, Wellesley, MA (US);

Mark Cooper, Cleveland, OH (US);

Assignees:

Northeastern University, Boston, MA (US);

Copernicus Therapeutics, Inc., Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07K 14/475 (2006.01); C12N 15/87 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01); C07K 14/47 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 48/0041 (2013.01); A61K 9/0043 (2013.01); A61K 9/51 (2013.01); A61K 47/48215 (2013.01); A61K 48/0075 (2013.01); C07K 14/475 (2013.01); C07K 14/4705 (2013.01); C12N 15/113 (2013.01); C12N 15/87 (2013.01); C12N 2310/11 (2013.01); C12N 2310/351 (2013.01); C12N 2830/008 (2013.01); C12N 2999/007 (2013.01);
Abstract

Disclosed herein are methods and compositions for the treatment of diseases of the CNS with nucleic acid nanoparticles. Compositions are also disclosed herein that utilize nucleic acid nanoparticles to treat conditions such as Parkinson's Disease. Furthermore, methods of intranasally administering the compacted nucleic acid nanoparticles for therapeutic purposes in the brain are disclosed.


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