The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2016
Filed:
Jan. 18, 2013
Applicant:
Regents of the University of Minnesota, St. Paul, MN (US);
Inventors:
Carston R. Wagner, St. Paul, MN (US);
Jae Chul Lee, Dublin, OH (US);
Sidath C. Kumarapperuma, Roseville, MN (US);
Assignee:
TYCHON BIOSCIENCE, LLC, Minneapolis, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 33/24 (2006.01); A61K 31/7088 (2006.01); C07D 475/08 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/48561 (2013.01); A61K 31/7088 (2013.01); A61K 33/24 (2013.01); A61K 47/481 (2013.01); A61K 47/48061 (2013.01); A61K 47/48092 (2013.01); A61K 47/48746 (2013.01); B82Y 5/00 (2013.01); C07D 475/08 (2013.01); Y10T 428/2982 (2015.01);
Abstract
The invention provides methods for attaching drugs, dyes or radiolabels to bis-MTX. This method can be used to prepare bis-MTX analogs that can be used to deliver agents, such as nanoparticles, drugs, dyes or radiolabels, to cells.