The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2016
Filed:
Nov. 22, 2013
Applicants:
University of Massachusetts, Shrewsbury, MA (US);
University of Miami, Miami, FL (US);
Inventors:
Marc Freeman, Barre, MA (US);
Stephan Zuchner, Pinecrest, FL (US);
Assignees:
University of Massachusetts, Boston, MA (US);
University of Miami, Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/713 (2006.01); A61K 31/7088 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/00 (2013.01); G01N 33/5058 (2013.01); G01N 33/566 (2013.01); G01N 33/6896 (2013.01); G01N 2500/04 (2013.01); G01N 2800/2814 (2013.01); G01N 2800/2835 (2013.01);
Abstract
The present disclosure provides methods for reducing axonal and/or synaptic degradation in neurons by modulating sterile α/Armadillo/Toll-Interleukin receptor homology domain protein (SARM) activity and/or expression.