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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9486403 B1

PDFFull Text
Date of Patent:
Nov. 08, 2016

Filed:

Dec. 16, 2013

Gel compositions

Applicant:

Laboratorios Ojer Pharma, S.l., Pamplona, ES;

Inventors:

Carlos González Ojer, Pamplona, ES;

Raquel Maria Da Costa Martins, Barcelona, ES;

Josep M. Suñé Negre, Barcelona, ES;

Montserrat Miñarro Carmona, Barcelona, ES;

Josep Ramon Ticó Grau, Barcelona, ES;

Encarna García Montoya, Barcelona, ES;

Pilar Pérez Lozano, Barcelona, ES;

Manel Roig Carreras, Calafell, ES;

Natalia Sánchez Porqueres, Barcelona, ES;

Assignee:

LABORATORIOS OJER PHARMA, S.L., Pamplona, ES;

Attorneys:

Peter B. Scull

Hamilton, DeSanctis & Cha, LLP

Primary Examiner:

Samantha Shterengarts

Int. Cl.
CPC ...
A61K 31/522 (2006.01); A61K 31/575 (2006.01); A61K 47/10 (2006.01); A61K 47/18 (2006.01); A61K 9/06 (2006.01); A61K 47/32 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 9/7015 (2013.01); A61K 31/522 (2013.01); A61K 31/575 (2013.01); A61K 47/10 (2013.01); A61K 47/18 (2013.01); A61K 47/32 (2013.01);
Abstract

The present invention provides a gel combination comprising: polycarbophil in an amount comprised from 1 to 5% by weight; polyvinylpirrolidone in an amount comprised from 4 to 8% by weight; glycerine in an amount comprised from 1 to 10% by weight; and propyleneglycolin an amount comprised from 20 to 40% by weight; wherein: the weight ratio between polyvinylpirrolidone:polycarbophil is comprised between 1:1 and 4:1, the weight ratio between glycerine:polycarbophil is comprised from 0.5:1 to 2:1, and the weight ratio propyleneglycol:polycarbophil is comprised from 8:1 to 20:1. The invention also provides transparent compositions comprising such gel combinations as well as processes for their preparation and the use thereof as a medicament. Due to the specific excipients, % by weight, and weight ratios forming the combination, the resulting compositions show a high bioadhesivity and bioavailability of the active ingredient, without toxic adverse effects.

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