The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2016
Filed:
Feb. 22, 2011
Smiti Vaid Gupta, Oakland Township, MI (US);
Enrique Martinez, Ii, Clinton Township, MI (US);
Fazlul H. Sarkar, Plymouth, MI (US);
Denis M. Callewaert, Metamora, MI (US);
Andreea Geamanu, Sterling Heights, MI (US);
Kevin Michael Patrie, Troy, MI (US);
Tiffany Capri Thomas, Scottsdale, AZ (US);
Andrew A. Dahl, Bloomfield Hills, MI (US);
Smiti Vaid Gupta, Oakland Township, MI (US);
Enrique Martinez, II, Clinton Township, MI (US);
Fazlul H. Sarkar, Plymouth, MI (US);
Denis M. Callewaert, Metamora, MI (US);
Andreea Geamanu, Sterling Heights, MI (US);
Kevin Michael Patrie, Troy, MI (US);
Tiffany Capri Thomas, Scottsdale, AZ (US);
Andrew A. Dahl, Bloomfield Hills, MI (US);
Other;
Abstract
A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogs of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.