The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Jan. 28, 2015
Case Western Reserve University, Cleveland, OH (US);
Anant Madabhushi, Beachwood, OH (US);
Pallavi Tiwari, Shaker Heights, OH (US);
Prateek Prasanna, Cleveland, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
Methods, apparatus, and other embodiments associated with distinguishing disease phenotypes using co-occurrence of local anisotropic gradient orientations (CoLIAGe) are described. One example apparatus includes a set of logics that acquires a radiologic image (e.g., MRI image) of a region of tissue demonstrating disease pathology (e.g., cancer), computes a gradient orientation for a pixel in the MRI image, computes a significant orientation for the pixel based on the gradient orientation, constructs a feature vector that captures a discretized entropy distribution for the image based on the significant orientation, and classifies the phenotype of the disease pathology based on the feature vector. Embodiments of example apparatus may generate and display a heatmap of entropy values for the image. Example methods and apparatus may operate substantially in real-time. Example methods and apparatus may operate in two or three dimensions.