The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Sep. 16, 2015
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Joanna L. Fueyo, Sandwich, MA (US);

Robert L. Angell, Salt Lake City, UT (US);

Robert R. Friedlander, Southbury, CT (US);

James R. Kraemer, Santa Fe, NM (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); G06F 19/00 (2011.01); A61B 5/055 (2006.01); A61B 5/00 (2006.01); A61B 6/03 (2006.01); A61B 6/00 (2006.01); G06F 17/30 (2006.01); G06K 9/46 (2006.01); G06K 9/62 (2006.01); G06T 7/00 (2006.01);
U.S. Cl.
CPC ...
G06F 19/321 (2013.01); A61B 5/055 (2013.01); A61B 5/411 (2013.01); A61B 5/417 (2013.01); A61B 6/037 (2013.01); A61B 6/501 (2013.01); A61B 6/56 (2013.01); A61B 6/563 (2013.01); A61B 6/566 (2013.01); G06F 17/30011 (2013.01); G06F 17/30864 (2013.01); G06F 19/345 (2013.01); G06F 19/3443 (2013.01); G06F 19/3481 (2013.01); G06K 9/46 (2013.01); G06K 9/6215 (2013.01); G06T 7/0012 (2013.01); G06F 19/324 (2013.01); G06K 2009/4666 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/10104 (2013.01); G06T 2207/30016 (2013.01);
Abstract

A computer implemented method, apparatus, and computer program product of determining mechanisms of action for therapies. A first set of brain scans for each subject in a plurality of subjects generated at a first time period and a second set of brain scans for each subject generated at a second time period are received. Each subject is diagnosed with a given condition and received a given therapy. A set of changes in the set of brain scans is identified for the each subject based on a comparison of a first set of regions of interest in the first set of scans for each subject with a second set of regions of interest in the second set of scans for each subject. A set of typical changes attributable to the given therapy is identified. A mechanism of action for the given therapy is generated based on the set of typical changes.


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