The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Feb. 21, 2013
Applicant:

Laboratory Corporation of America Holdings, Burlington, NC (US);

Inventors:

Dwight Lyman Anderson, Minneapolis, MN (US);

Andrew J. Conrad, Malibu, CA (US);

Stephen Erickson, White Bear Township, MN (US);

Jose S. Gil, Winnetka, CA (US);

Ben Barrett Hopkins, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); C12Q 1/70 (2013.01); G01N 33/569 (2013.01); G01N 33/581 (2013.01);
Abstract

Disclosed are methods and systems for the isolation and detection of microbes from a sample. The use of binding agents for isolation of a microbe of interest from a sample are described. In certain embodiments, the methods use ribosome-based and/or bacteriophage-based amplification of the signal in detection of bacteria and other microorganisms. For example, embodiments of the present invention can achieve total amplification of at least 10,000 from a single infected cell.


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