The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Jan. 12, 2012
Applicants:

Takuya Yotani, Ibaraki, JP;

Koji Ushizawa, Tokyo, JP;

Inventors:

Takuya Yotani, Ibaraki, JP;

Koji Ushizawa, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12Q 1/68 (2006.01); B01D 15/00 (2006.01); C12N 15/10 (2006.01); G01N 30/96 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/101 (2013.01); C12Q 1/6806 (2013.01); G01N 30/96 (2013.01); Y10T 436/143333 (2015.01);
Abstract

The present invention provides eluent for ion-exchange chromatography, wherein the eluent allows separation and detection of a target nucleic acid such as a PCR-amplified product, a restriction enzyme fragment of the PCR-amplified product, or a restriction enzyme fragment of a nucleic acid in a short time with high separation performance. The present invention also provides a method of analyzing nucleic acid chains by ion-exchange chromatography using the eluent. The present invention provides an eluent for ion-exchange chromatography comprising a guanidine salt derived from guanidine represented by the following formula (1):


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