The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Jun. 30, 2015
Applicants:

Siddharth G. Kamath, Tampa, FL (US);

Chad Dickey, Tampa, FL (US);

Basil Cherpelis, Tampa, FL (US);

Inventors:

Siddharth G. Kamath, Tampa, FL (US);

Chad Dickey, Tampa, FL (US);

Basil Cherpelis, Tampa, FL (US);

Assignee:

UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12P 21/06 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01); C12N 5/0793 (2010.01); C12N 15/65 (2006.01); C12N 15/113 (2010.01); A61K 35/30 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0619 (2013.01); A61K 35/30 (2013.01); C12N 15/113 (2013.01); C12N 15/65 (2013.01); C12N 2310/122 (2013.01); C12N 2506/1307 (2013.01);
Abstract

The subject invention concerns materials and methods for conversion of non-neuronal cells into neurons. The subject invention also concerns methods for screening drugs and other compounds for activity in treating Alzheimer's disease using neuronal cells produced using the subject invention. The subject invention also concerns neuronal cells that have been produced using the methods of the invention. The subject invention also concerns methods for evaluating therapeutic treatment for efficacy in a person or animal having Alzheimer's disease or other neurodegenerative diseases. The subject invention also concerns methods of treating Alzheimer's disease or other neurodegenerative diseases or conditions in a person or animal.


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