The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Dec. 10, 2012
Applicants:

The Rockefeller University, New York, NY (US);

Sloan-kettering Institute for Cancer Research, New York, NY (US);

Inventors:

Jeffrey Ravetch, New York, NY (US);

Andrew Pincetic, New York, NY (US);

Ping Wang, New York, NY (US);

Sam Danishefsky, Englewood, NJ (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 16/18 (2006.01); A61K 31/7028 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07H 7/02 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 31/7028 (2013.01); A61K 38/16 (2013.01); A61K 38/1709 (2013.01); C07H 7/02 (2013.01); C07K 14/47 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2316/95 (2013.01);
Abstract

Polypeptides that bind to DC-SIGN and/or its homologues and methods for using such peptides for the treatment of various disorders are described. DC-SIGN and its homologues are receptors that bind IgG antibodies or Fc fragments and mediate intravenous immunoglobulin (IVIG)-related reversal of inflammation associated with various immune disorders.


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