The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Mar. 12, 2015
Applicant:

Board of Regents, University of Texas System, Austin, TX (US);

Inventors:

Philip Jones, Houston, TX (US);

Maria Emilia DiFrancesco, Houston, TX (US);

Alessia Petrocchi, Houston, TX (US);

Christopher L. Carroll, Houston, TX (US);

Joe Marszalek, Houston, TX (US);

Barbara Czako, Houston, TX (US);

Ryan Johnson, Houston, TX (US);

Jay Theroff, Houston, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/454 (2006.01); C07D 513/04 (2006.01); C07D 413/04 (2006.01); C07D 417/14 (2006.01); C07D 417/04 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01); C07D 471/04 (2006.01); A61K 31/4245 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.


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