The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Feb. 09, 2015
Applicant:
Duquesne University of the Holy Ghost, Pittsburgh, PA (US);
Inventors:
Aleem Gangjee, Allison Park, PA (US);
Larry H. Matherly, Novi, MI (US);
Assignees:
Duquesne University of the Holy Ghost, Pittsburgh, PA (US);
Wayne State University, Detroit, MI (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract
Pyrrolo[2,3-d]pyrimidine derivatives, and pharmaceutical acceptable salts thereof, useful in therapeutically treating patients with cancer are disclosed. These compounds selectively target folate receptors (FR) of cancerous tumor cells and inhibit purine synthesis and hence, DNA synthesis.