The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
May. 13, 2015
Eisai R&d Management Co., Ltd., Tokyo, JP;
Gregg F. Keaney, Lexington, MA (US);
John Wang, Andover, MA (US);
Baudouin Gerard, Belmont, MA (US);
Kenzo Arai, Tsukubamirai, JP;
Xiang Liu, Winchester, MA (US);
Guo Zhu Zheng, Lexington, MA (US);
Kazunobu Kira, Ushiku, JP;
Parcharee Tivitmahaisoon, Boston, MA (US);
Sudeep Prajapati, Somerville, MA (US);
Nicholas C. Gearhart, Durango, CO (US);
Yoshihiko Kotake, Tsuchirua, JP;
Satoshi Nagao, Tsukuba, JP;
Regina Mikie Kanada Sonobe, Nagareyama, JP;
Masayuki Miyano, Tsukubamirai, JP;
Norio Murai, Tsukuba, JP;
Silvia Buonamici, Boston, MA (US);
Lihua Yu, Acton, MA (US);
Eunice Sun Park, Arlington, MA (US);
Betty Chan, Harvard, MA (US);
Peter G. Smith, Arlington, MA (US);
Michael P. Thomas, Stoneham, MA (US);
Ermira Pazolli, Wayland, MA (US);
Kian Huat Lim, Burlington, MA (US);
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.