The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Apr. 07, 2014
Jonathan Daniel Heller, San Francisco, FL (US);
Qingqi Chen, Chapel Hill, NC (US);
Rocio Alejandra Lopez, Raleigh, NC (US);
Amanda Jean Morris, Graham, NC (US);
Jonathan Daniel Heller, San Francisco, FL (US);
Qingqi Chen, Chapel Hill, NC (US);
Rocio Alejandra Lopez, Raleigh, NC (US);
Amanda Jean Morris, Graham, NC (US);
ERimos Pharmaceuticals, LLC, Houston, TX (US);
Abstract
The present invention relates to nordihydroguaiaretic acid derivative compounds, namely, butane bridge modified nordihydroguaiaretic acid (NDGA) compounds and butane bridge modified tetra-O-substituted NDGA compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, metabolic diseases, such as diabetes and hypertension, or a proliferative disease, such as diverse types of cancers.