The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

May. 11, 2012
Applicants:

Marcus F. Boehm, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Enugurthi Brahmachary, San Diego, CA (US);

Manisha Moorjani, San Diego, CA (US);

Junko Tamiya, Carlsbad, CA (US);

Liming Huang, San Diego, CA (US);

Adam Richard Yeager, La Mesa, CA (US);

Inventors:

Marcus F. Boehm, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Enugurthi Brahmachary, San Diego, CA (US);

Manisha Moorjani, San Diego, CA (US);

Junko Tamiya, Carlsbad, CA (US);

Liming Huang, San Diego, CA (US);

Adam Richard Yeager, La Mesa, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 285/12 (2006.01); C07D 417/10 (2006.01); C07D 333/24 (2006.01); C07D 277/30 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 285/12 (2013.01); C07D 277/30 (2013.01); C07D 333/24 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01);
Abstract

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.


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