The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Nov. 18, 2013
Applicant:

Serene Oncology, Llc, New York, NY (US);

Inventors:

Nigel R. Stevenson, Sugar Hill, GA (US);

Jaime Simon, Angleton, TX (US);

Gilbert R. Gonzales, Tucson, AZ (US);

Assignee:

Serene, LLC, The Woodlands, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/08 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 51/083 (2013.01); A61K 51/0482 (2013.01);
Abstract

Tin-117m somatoostatin analogs or antagonist are used to treat tumors and symptoms associated with these tumors which express somatostatin receptors, such as gastroenteropancreatic neuroendocrine tumors. The tin-117m somatostatin receptor binding compounds can be administered at a dosage which is effectively apoptotic and not necrotic. Also, if desired, it can be administered at a dose that is necrotic and/or induces necrosis, but only to cells within 290 microns of the tin-117m atom. A novel somatostatin analog is also disclosed, as well as novel methods to produce the tin labeled analogs and antagonists.


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