The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2016

Filed:

Jul. 10, 2013
Applicant:

Baseclick Gmbh, Tutzing, DE;

Inventor:

Thomas Carell, Krailling, DE;

Assignee:

Baseclick GmbH, Tutzing, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 47/48 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); C07H 19/16 (2006.01); C07H 19/04 (2006.01); C07H 19/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48038 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); C07H 19/04 (2013.01); C07H 19/06 (2013.01); C07H 19/16 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2320/32 (2013.01);
Abstract

The present invention refers to a conjugate comprising at least one polyunsaturated fatty acid residue, particularly an arachidonic acid residue, more particularly an anandamide (arachidonoyl ethanol amide) residue and covalently bound thereto at least one nucleosidic component selected from nucleic acids, nucleosides and nucleotides. This conjugate is suitable for the transfection of cells such as mammalian cells including human cells with high efficacy. Thus, a new delivery vehicle for therapeutic molecules including antisense molecules, siRNA molecules, miRNA molecules, antagomirs or precursors of such molecules, as well as the therapeutic nucleosides or nucleotides, is provided.


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