The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Apr. 24, 2015
Applicant:
Georgetown University, Washington, DC (US);
Inventors:
Esther H. Chang, Potomac, MD (US);
Kathleen F. Pirollo, Rockville, MD (US);
Assignee:
Georgetown University, Washington, DC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 47/48 (2006.01); A61K 49/18 (2006.01); A61K 47/42 (2006.01); A61K 39/395 (2006.01); A61K 41/00 (2006.01); A61K 31/4025 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61K 9/0019 (2013.01); A61K 9/127 (2013.01); A61K 9/1272 (2013.01); A61K 31/4025 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 39/39558 (2013.01); A61K 41/0038 (2013.01); A61K 47/48538 (2013.01); A61K 47/48823 (2013.01); A61K 49/1812 (2013.01); A61K 2039/505 (2013.01);
Abstract
A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex.