The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2016
Filed:
Jan. 29, 2015
Applicant:
Allergan, Inc., Irvine, CA (US);
Inventors:
Hongwen M. Rivers, San Diego, CA (US);
Lon T. Spada, Walnut, CA (US);
Michelle Luu, Anaheim, CA (US);
Assignee:
Allergan, Inc., Irvine, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2006.01); A61K 47/48 (2006.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0051 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/34 (2013.01); A61K 47/48046 (2013.01); A61K 47/48246 (2013.01); A61K 47/48323 (2013.01); A61K 48/0075 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3515 (2013.01);
Abstract
The present invention provides an ocular implant of siRNA complexed with a transfection agent such as cationic lipids and short cell penetration peptides, wherein the complex is associated with a biocompatible polymer. The biocompatible polymer includes a polymeric matrix configured to release the complex into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease.