The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2016
Filed:
Apr. 11, 2012
Applicants:
Jonathan G. Seidman, Milton, MA (US);
Christine E. Seidman, Milton, MA (US);
Daniel E. Herman, Cambridge, MA (US);
Inventors:
Jonathan G. Seidman, Milton, MA (US);
Christine E. Seidman, Milton, MA (US);
Daniel E. Herman, Cambridge, MA (US);
Assignees:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12N 9/12 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Provided herein are diagnostic markers and methods for identifying a subject having an increased susceptibility for developing or having dilated cardiomyopathy. The method comprises determining if the subject has a mutation in the TTN nucleic as acid or titin polypeptide. Further provided herein are methods of treating subjects having or at risk of having dilated cardiomyopathy.