The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2016
Filed:
Jul. 22, 2014
Applicant:
Max-planck-gesellschaft Zur Foerderung Der Wissenschaften E.v., Munich, DE;
Inventors:
Thomas Tuschl, New York, NY (US);
Javier Martinez, New York, NY (US);
Agnieszka Patkaniowska, New York, NY (US);
Henning Urlaub, Goettingen, DE;
Reinhard Luehrmann, Marburg-Michelbach, DE;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 47/48 (2006.01); C07K 14/47 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 47/48092 (2013.01); A61K 47/48146 (2013.01); C07K 14/4705 (2013.01); C07K 19/00 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3513 (2013.01); C12N 2330/30 (2013.01);
Abstract
The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.