The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

May. 22, 2015
Applicants:

Allison Coffin, Vancouver, WA (US);

Joseph Harding, Pullman, WA (US);

Leen Kawas, Seattle, WA (US);

Phillip Uribe, Vancouver, WA (US);

Inventors:

Allison Coffin, Vancouver, WA (US);

Joseph Harding, Pullman, WA (US);

Leen Kawas, Seattle, WA (US);

Phillip Uribe, Vancouver, WA (US);

Assignee:

Washington State University, Pullman, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 16/00 (2006.01); C07K 14/475 (2006.01); C07K 5/065 (2006.01); C07K 5/062 (2006.01); C07K 5/072 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4753 (2013.01); C07K 5/0606 (2013.01); C07K 5/06078 (2013.01); C07K 5/06104 (2013.01); C07K 5/06113 (2013.01); A61K 38/00 (2013.01);
Abstract

A novel method of preventing or reducing ototoxicity in vertebrates undergoing treatment with therapeutically effective amounts of platinum-based chemotherapeutic agents such as cisplatin or aminoglycoside antibiotics is disclosed herein. The method(s) comprise administering an effective amount of an otoprotective agent comprising Dihexa prior to, concomitantly with, or subsequently to administration of the platinum-based chemotherapeutic agent or aminoglycoside antibiotic.


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