The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Feb. 20, 2013
Applicant:

Bayer Intellectual Property Gmbh, Monheim, DE;

Inventors:

Mario Lobell, Wuppertal, DE;

Walter Hübsch, Wuppertal, DE;

Hartmut Schirok, Langenfeld, DE;

Mélanie Héroult, Düsseldorf, DE;

Dirk Brohm, Mettmann, DE;

Marie-Pierre Collin, Wuppertal, DE;

Sylvia Grünewald, Berlin, DE;

Klemens Lustig, Wuppertal, DE;

Ulf Bömer, Glienicke, DE;

Verena Voehringer, Wolfegg, DE;

Niels Lindner, Wuppertal, DE;

Assignee:

BAYER INTELLETUAL PROPERTY GMBH, Monheim am Rhein, DE;

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); A61K 31/53 (2006.01); A61K 31/4985 (2006.01); A61K 31/4427 (2006.01); A61P 35/00 (2006.01); A61K 31/5377 (2006.01); A61K 31/5513 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/5513 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 519/00 (2013.01);
Abstract

This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.


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