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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9475812 B1

PDFFull Text
Expired
Date of Patent:
Oct. 25, 2016

Filed:

Jun. 04, 2012

Pyridonaphthyridine type dual pi3k and mtor inhibitor and its preparation and use

Applicants:

Frank Wu, Jinan, CN;

Yan Zhang, Jinan, CN;

Inventors:

Frank Wu, Jinan, CN;

Yan Zhang, Jinan, CN;

Assignee:

Xuanzhu Pharma Co., Ltd., Jinan, CN;

Attorneys:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Ingrid A. Beattie

Primary Examiner:

Rita Desai

Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/496 (2006.01); A61K 31/4545 (2006.01); A61K 31/4375 (2006.01); C07D 519/00 (2006.01); A61K 9/00 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61K 9/00 (2013.01); A61K 31/4375 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R, R, R, R, R, R, Rand X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.

Find Patent Forward Citations

Wu, Frank. (2016). Pyridonaphthyridine type dual pi3k and mtor inhibitor and its preparation and use (U.S. Patent No. 9475812). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9475812

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