The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2016
Filed:
Sep. 15, 2015
Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;
Abbvie Inc., North Chicago, IL (US);
Hervé Geneste, Ludwigshafen, DE;
Michael Ochse, Ludwigshafen, DE;
Karla Drescher, Ludwigshafen, DE;
Berthold Behl, Ludwigshafen, DE;
Loic Laplanche, Ludwigshafen, DE;
Jürgen Dinges, North Chicago, IL (US);
Clarissa Jakob, North Chicago, IL (US);
AbbVie Deutschland GmbH & Co. KG, Wiesbaden, DE;
AbbVie Inc., North Chicago, IL (US);
Abstract
The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof: In formula I the variables Het, A, X, Y, Z, R1, R2, R3, R4, R5 and Q are as defined in the claims. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A. Thus, the invention also relates to the use of the compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.