The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Dec. 19, 2012
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Yong-Jin Wu, Madison, CT (US);

Jason M. Guernon, Moodus, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 279/06 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 279/06 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

Compounds of formula (I), including pharmaceutically acceptable salts thereof, are set forth herein: wherein Rand Rare independently hydrogen, or —CH; or Rand Rcan join together in a ring by adding —(CH)—; Ris hydrogen or C-Calkyl; Y and Z are independently a C-C-aryl group or a 5-10 membered heterocyclic group which can be further substituted with from 0-3 substituents selected from the group of halogen, hydroxy, amino, Calkylamino, Cdialkylamino, haloCalkyl, CN, C-Calkyl or cycloalkyl, C-Calkoxy, —C═OCalkyl, —SOCalkyl, and C-Calkynyl; A is selected from the group of phenyl, benzyl, oxazolyl, thiazolyl, isoxazolyl, imidazolyl, pyrazolyl, pyridyl, pyrimidinyl, and pyrazinyl groups which can be further substituted with from 0-3 substituents selected from the group of halogen, hydroxy, amino, Calkylamino, Cdialkylamino, haloCalkyl, hydroxyCalkyl, CN, C-Calkyl or cycloalkyl, C-Calkoxy, and C-Calkynyl; L is —NHCO— or is a single bond; and L and Z together can be absent.


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